Supreme Pizza Casserole

If you love pizza night but want something even heartier, this Supreme Pizza Casserole is the perfect recipe for you. Packed with pasta, gooey cheese, savory meats, and all your favorite pizza toppings, this dish combines the best of both worlds—pizza and casserole. It’s an easy, family-friendly meal that’s perfect for weeknights, potlucks, or even game day gatherings.

Ingredients

• 12 ounces penne or medium pasta
• ½ pound Italian sausage or lean ground beef
• 1 medium onion, diced
• 3 cloves garlic, minced
• 2 cups pizza toppings (bell peppers, mushrooms, olives, etc.)
• 14 ounces canned diced tomatoes, drained
• 1 teaspoon dried oregano
• 1 teaspoon Italian seasoning
• 14 ounces pizza sauce
• 2 cups marinara sauce or pasta sauce
• 3 cups shredded cheddar cheese blend
• 1 cup sliced pepperoni, divided
• ¼ cup shredded Parmesan cheese

Instructions

1. Preheat your oven to 425°F.
2. Cook the pasta according to package directions until al dente, then drain and set aside.
3. In a large skillet, brown the Italian sausage (or beef) with diced onion and garlic over medium-high heat. Drain excess fat.
4. Add your preferred pizza toppings and cook for about 3-4 minutes, just until the vegetables begin to soften.
5. Stir in the drained tomatoes, oregano, Italian seasoning, pizza sauce, and marinara sauce. Let it simmer for 5 minutes to blend the flavors.
6. Combine the cooked pasta with the sauce mixture, along with half of the pepperoni slices. Toss well to coat.
7. Pour everything into a greased 9×13-inch baking dish.
8. Top with the shredded cheddar cheese blend, remaining pepperoni, and Parmesan cheese.
9. Bake uncovered for 18–22 minutes, or until the cheese is bubbly and golden brown on top.
10. Let it rest for a few minutes before serving to allow the casserole to set slightly.

Serving and Storage Tips

Serve your Supreme Pizza Casserole hot, straight from the oven, with a fresh green salad or garlic bread on the side. To store leftovers, let the casserole cool completely, then cover tightly and refrigerate for up to 4 days. Reheat individual portions in the microwave or the whole dish in a 350°F oven until heated through. For longer storage, freeze portions in airtight containers for up to 2 months.

Variations

1. Meat Lovers Version: Add bacon, ham, and sausage for a protein-packed twist.
2. Veggie Lover’s Casserole: Load it with mushrooms, zucchini, bell peppers, and spinach.
3. Hawaiian Style: Add diced ham and pineapple chunks for a sweet-and-savory combination.
4. BBQ Chicken Pizza Bake: Replace marinara with BBQ sauce and use shredded chicken.
5. Spicy Supreme: Add jalapeños, crushed red pepper flakes, and spicy Italian sausage.
6. White Pizza Casserole: Skip the marinara and use Alfredo sauce instead.
7. Cheeseburger Casserole: Use ground beef, cheddar cheese, and a drizzle of ketchup and mustard.
8. Philly Cheesesteak Casserole: Add thinly sliced steak, peppers, onions, and provolone cheese.
9. Breakfast Pizza Casserole: Include scrambled eggs, crumbled bacon, and hash browns.
10. Greek Style: Add black olives, feta cheese, red onion, and spinach.
11. Four Cheese Supreme: Mix mozzarella, provolone, cheddar, and Parmesan.
12. Low-Carb Option: Replace pasta with zucchini noodles or cauliflower florets.
13. Buffalo Chicken Supreme: Use buffalo sauce, shredded chicken, and blue cheese crumbles.
14. Taco Pizza Casserole: Replace Italian seasoning with taco spices and add jalapeños and salsa.
15. Pepperoni Lover’s Bake: Double the pepperoni and add extra mozzarella for a classic flavor.

FAQs

1. Can I make this casserole ahead of time?
Yes, assemble it up to a day in advance, cover, and refrigerate. Bake when ready to serve.

2. Can I use other pasta shapes?
Absolutely. Rotini, rigatoni, or ziti all work well.

3. What are the best pizza toppings for this recipe?
Try mushrooms, onions, bell peppers, olives, or cooked sausage for a true supreme flavor.

4. Can I freeze this casserole?
Yes, freeze before or after baking. If frozen before, thaw overnight and bake as directed.

5. How do I make it vegetarian?
Skip the meat and load up on vegetables like spinach, tomatoes, and zucchini.

6. What cheese works best?
A mix of mozzarella, cheddar, and Parmesan gives the best texture and flavor.

7. Can I use store-bought pizza sauce?
Yes, any brand of pizza or marinara sauce will work fine.

8. How long does it last in the fridge?
Up to 4 days when stored in an airtight container.

9. Can I add more protein?
Yes, chicken, turkey, or extra sausage can be added.

10. What can I serve with it?
Garlic bread, Caesar salad, or roasted vegetables pair perfectly.

This Supreme Pizza Casserole is a cheesy, crowd-pleasing meal that delivers all the bold flavors of a classic pizza in comforting casserole form. It’s easy to prepare, endlessly customizable, and perfect for busy weeknights or family gatherings. Whether you’re a meat lover, a veggie enthusiast, or simply a fan of gooey, melty cheese, this dish will quickly become a favorite in your dinner rotation.

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