Pizza Casserole

Pizza meets pasta in this delightful Pizza Casserole recipe that promises to tantalize your taste buds. Combining the comforting elements of a pasta bake with the flavors of your favorite pizza, this hearty dish is ideal for family dinners or potluck gatherings. Let’s dive into the recipe and discover how to create this mouthwatering masterpiece.


  • 1 pound ground beef
  • Salt and pepper to taste
  • ½ tablespoon olive oil
  • ½ cup onion, chopped
  • 1 teaspoon minced garlic
  • 2 cups shredded mozzarella cheese (divided)
  • 16 ounces Rotini or Penne pasta (uncooked)
  • 24 ounces spaghetti or marinara sauce
  • 1 tablespoon Italian seasoning
  • 1 cup pepperoni
  • ½ teaspoon Italian seasoning
  • Fresh shredded parmesan for garnish (optional)


  1. Preheat and Prepare: Preheat your oven to 350°F. Spray a 9×13-inch pan with nonstick spray to prevent sticking.
  2. Cook the Pasta: Cook the pasta according to package directions for al dente. Once cooked, drain and set aside.
  3. Prepare the Meat Mixture: In a large skillet, heat olive oil over medium heat. Add ground beef, onions, and garlic, seasoned with salt and pepper. Cook until the beef is browned and no longer pink. Drain any excess grease.
  4. Combine Ingredients: Stir in the spaghetti sauce and 1 tablespoon of Italian seasoning into the ground beef mixture. Remove from heat.
  5. Mix Pasta and Meat: Add the cooked pasta and 1 cup of shredded mozzarella cheese to the meat mixture. Stir well to combine all ingredients evenly.
  6. Assemble the Casserole: Pour the pasta and meat mixture into the prepared 9×13-inch pan, spreading it out evenly.
  7. Add Cheese and Pepperoni: Sprinkle the remaining 1 cup of shredded mozzarella cheese over the top of the casserole. Arrange the pepperoni slices on top of the cheese.
  8. Season and Bake: Sprinkle ½ teaspoon of Italian seasoning over the casserole. Bake uncovered for 25-30 minutes, or until the cheese is melted and bubbly.
  9. Serve and Enjoy: Once baked to perfection, remove the casserole from the oven. Optionally, garnish with fresh shredded parmesan before serving.

Nutritional Information:

  • Prep Time: 10 min
  • Cooking Time: 30 min
  • Total Time: 40 min
  • Calories: 450
  • Servings: 8

Serving and Storage Tips:

Serving Suggestions:

  1. Garnish with Fresh Herbs: Before serving, sprinkle some freshly chopped basil or parsley over the casserole to add a burst of freshness and color.
  2. Pair with Garlic Bread: Serve the Pizza Casserole alongside warm garlic bread or garlic knots for a complete and satisfying meal.
  3. Add a Side Salad: Balance out the richness of the casserole with a crisp green salad dressed with balsamic vinaigrette or Italian dressing.
  4. Customize Toppings: Encourage guests to customize their servings by offering additional toppings such as olives, bell peppers, or mushrooms on the side.
  5. Serve with Dipping Sauce: Provide marinara sauce or ranch dressing on the side for dipping, enhancing the pizza-inspired experience.

Storage Tips:

  1. Refrigeration: Allow any leftovers to cool completely before transferring them to an airtight container. Refrigerate within two hours of cooking and consume within 3-4 days.
  2. Freezing: Pizza Casserole can be frozen for longer storage. Wrap individual portions or the entire casserole tightly in plastic wrap and aluminum foil before placing in the freezer. Properly stored, it will maintain quality for up to 2-3 months.
  3. Reheating: To reheat refrigerated portions, microwave individual servings for 1-2 minutes or until heated through. For frozen portions, thaw overnight in the refrigerator before reheating in the oven at 350°F for 20-25 minutes, or until hot and bubbly.
  4. Revitalize Texture: If the casserole seems dry after reheating, drizzle a little extra marinara sauce over the top or sprinkle with a touch of water before reheating to help restore moisture.

By following these serving and storage tips, you can ensure that your Pizza Casserole remains delicious and enjoyable, whether served fresh out of the oven or reheated as a convenient leftover meal.


  1. Vegetarian Option: Substitute the ground beef with plant-based crumbles or a medley of your favorite vegetables such as mushrooms, bell peppers, and olives for a meat-free alternative.
  2. Four Cheese Blend: Experiment with different cheese combinations such as adding provolone, cheddar, or fontina along with the mozzarella for an extra cheesy twist.
  3. Spicy Kick: Kick up the heat by incorporating sliced jalapeños or crushed red pepper flakes into the meat mixture for a spicy variation.
  4. White Pizza Casserole: Replace the traditional tomato-based sauce with a creamy Alfredo sauce and top with spinach, artichoke hearts, and a blend of Italian cheeses for a decadent white pizza-inspired dish.
  5. Buffalo Chicken Casserole: Swap out the ground beef for shredded cooked chicken tossed in buffalo sauce. Layer with blue cheese crumbles and drizzle with ranch dressing for a flavorful buffalo chicken pizza casserole.
  6. Hawaiian Twist: Add diced pineapple and ham to the casserole for a tropical Hawaiian-inspired flavor profile. Top with a sprinkle of shredded coconut for an extra touch of sweetness.
  7. Mediterranean Style: Incorporate Mediterranean flavors by using a pesto sauce base instead of marinara. Add ingredients like sun-dried tomatoes, Kalamata olives, and feta cheese for a Mediterranean-inspired twist.
  8. Tex-Mex Fusion: Infuse Tex-Mex flair by substituting the Italian seasoning with taco seasoning and adding black beans, corn, and diced green chilies to the meat mixture. Top with sliced avocado and a dollop of sour cream before serving.
  9. Breakfast Casserole: Transform this dish into a breakfast favorite by using cooked breakfast sausage or bacon instead of ground beef. Add beaten eggs and milk to the pasta mixture before baking for a hearty breakfast casserole.
  10. Stuffed Pepperoni Rolls: Roll the pasta and meat mixture inside refrigerated pizza dough to create stuffed pepperoni rolls. Bake until golden brown for a handheld twist on the classic casserole.


  1. Can I use different types of pasta for this recipe? Yes, feel free to experiment with your favorite pasta shapes such as penne, rigatoni, or even spaghetti noodles.
  2. Can I make this casserole ahead of time? Absolutely! You can prepare the casserole up to a day in advance, cover tightly with foil, and refrigerate until ready to bake.
  3. Can I freeze the Pizza Casserole before baking? Yes, you can assemble the casserole, cover it tightly, and freeze it for later use. Allow it to thaw in the refrigerator overnight before baking as directed.
  4. Can I customize the toppings to suit my preferences? Of course! Feel free to add or omit toppings according to your taste preferences or dietary restrictions.
  5. How do I prevent the casserole from becoming dry when reheating? Adding a splash of additional marinara sauce or covering the casserole with foil while reheating can help retain moisture.
  6. Can I make a smaller portion of this recipe? Yes, you can halve the ingredients and use a smaller baking dish for a smaller portion.
  7. Is this recipe kid-friendly? Absolutely! Kids love the familiar flavors of pizza in casserole form, making it a family-friendly meal.
  8. Can I use pre-cooked pasta for this recipe? While it’s best to use uncooked pasta for optimal texture, you can use leftover cooked pasta if desired. Just reduce the baking time accordingly.
  9. Can I substitute ground turkey or chicken for the ground beef? Yes, ground turkey or chicken can be used as a leaner alternative to ground beef in this recipe.
  10. Can I add additional vegetables to the casserole? Certainly! Feel free to add diced vegetables such as zucchini, spinach, or mushrooms to boost the nutritional content of the casserole.

Indulge in the delightful fusion of pizza and pasta with this easy-to-make Pizza Casserole. Whether it’s a cozy family dinner or a potluck gathering with friends, this crowd-pleasing dish is guaranteed to satisfy cravings and bring joy to every bite. Enjoy the comforting flavors and hearty textures of this irresistible casserole!