Chicken Spaghetti Casserole

Satisfy your cravings for comfort food with this creamy and flavorful Chicken Spaghetti Casserole recipe. Loaded with tender chicken, al dente spaghetti, and a creamy blend of soups and cheese, this casserole is the ultimate family-friendly dish. Perfect for busy weeknights or potluck gatherings, it’s sure to become a staple in your recipe collection.


  • 8 oz spaghetti noodles, cooked and drained
  • 2 cups cooked chicken, shredded
  • 1 can cream of mushroom soup
  • 1 can cream of chicken soup
  • 1 cup sour cream
  • 1 cup chicken broth
  • 1 cup cheddar cheese, shredded
  • 1 small onion, diced
  • 1 bell pepper, diced
  • 1 teaspoon garlic powder
  • 1 teaspoon onion powder
  • Salt and pepper to taste
  • 1/2 cup Parmesan cheese, for topping
  • 1/2 cup breadcrumbs, for topping


  1. Preheat Oven: Preheat your oven to 350°F (175°C) and grease a 9×13 inch baking dish.
  2. Prepare Casserole Mixture: In a large bowl, combine the cream of mushroom soup, cream of chicken soup, sour cream, and chicken broth until smooth.
  3. Add Ingredients: Stir in the cooked spaghetti, shredded chicken, diced onion, diced bell pepper, cheddar cheese, garlic powder, onion powder, salt, and pepper until well combined.
  4. Transfer to Baking Dish: Transfer the mixture to the prepared baking dish, spreading it out evenly.
  5. Prepare Topping: In a small bowl, mix together the breadcrumbs and Parmesan cheese. Sprinkle this topping evenly over the casserole.
  6. Bake: Place the casserole in the preheated oven and bake for 25-30 minutes, or until the topping is golden brown and the casserole is bubbling around the edges.
  7. Serve: Remove from the oven and let it cool for a few minutes before serving. Enjoy the creamy, comforting goodness of this chicken spaghetti casserole!

Nutritional Information:

  • Prep Time: 15 minutes
  • Cooking Time: 30 minutes
  • Total Time: 45 minutes
  • Calories: 350 per serving
  • Servings: 6

Serving and Storage Tips:

  1. Serve Hot and Fresh: Chicken Spaghetti Casserole is best served hot out of the oven when it’s at its creamiest and most flavorful.
  2. Let it Rest: Allow the casserole to rest for a few minutes after baking to allow the flavors to meld together and for easier serving.
  3. Garnish Before Serving: Sprinkle freshly chopped parsley or green onions over the casserole just before serving for a pop of color and added freshness.
  4. Pair with Sides: Serve the casserole with a side salad, steamed vegetables, or garlic bread to round out the meal and add variety.
  5. Store Leftovers Properly: If you have leftovers, store them in an airtight container in the refrigerator for up to 3-4 days. Ensure the casserole has cooled completely before refrigerating.
  6. Reheat Gently: To reheat leftovers, place individual portions in a microwave-safe dish and heat on medium power for 1-2 minutes, or until heated through. Alternatively, reheat in the oven at 350°F (175°C) for 15-20 minutes.
  7. Freeze for Future Meals: Chicken Spaghetti Casserole can be frozen for longer storage. Wrap the cooled casserole tightly in plastic wrap and aluminum foil, or transfer it to a freezer-safe container. Freeze for up to 2-3 months.
  8. Thaw Before Reheating: When ready to enjoy frozen casserole, thaw it overnight in the refrigerator before reheating. This helps maintain the texture and flavor of the dish.
  9. Reheat from Frozen: If reheating from frozen, bake the casserole, covered, in a preheated oven at 350°F (175°C) for 30-40 minutes, or until heated through. Remove the cover during the last 10 minutes of baking to allow the topping to crisp up.
  10. Portion for Convenience: Consider portioning the casserole into individual servings before freezing for easier reheating and serving.

By following these serving and storage tips, you can ensure that your Chicken Spaghetti Casserole remains delicious and satisfying, whether freshly baked or enjoyed as leftovers.


  1. Vegetarian Option: Replace the chicken with cooked vegetables such as mushrooms, bell peppers, and spinach for a delicious vegetarian version of the casserole.
  2. Tex-Mex Twist: Add a can of diced tomatoes with green chilies and a sprinkle of taco seasoning to the casserole mixture for a Tex-Mex flavor profile. Top with sliced avocado and cilantro before serving.
  3. Buffalo Chicken: Mix cooked shredded chicken with buffalo sauce before adding it to the casserole mixture. Serve with a drizzle of ranch dressing for a spicy kick.
  4. Italian-Inspired: Use Italian seasoning instead of garlic and onion powder, and add diced tomatoes, fresh basil, and mozzarella cheese to the casserole mixture. Top with grated Parmesan cheese before baking.
  5. Mediterranean Flavors: Incorporate ingredients like sun-dried tomatoes, Kalamata olives, and feta cheese into the casserole mixture. Sprinkle with chopped fresh parsley before serving.
  6. Broccoli and Cheese: Add steamed broccoli florets and extra shredded cheddar cheese to the casserole mixture for a cheesy and veggie-packed variation.
  7. Spicy Sausage: Substitute cooked and crumbled spicy Italian sausage for the chicken to add a bold and zesty flavor to the casserole.
  8. Pesto Chicken: Mix cooked shredded chicken with pesto sauce before adding it to the casserole mixture. Top with toasted pine nuts for added crunch.
  9. Greek-Inspired: Use Greek yogurt instead of sour cream, and add ingredients like artichoke hearts, black olives, and feta cheese to the casserole mixture. Serve with a side of tzatziki sauce for dipping.
  10. Taco Casserole: Season the chicken with taco seasoning and mix with cooked black beans and corn kernels before adding to the casserole mixture. Top with crushed tortilla chips before baking for a crunchy Tex-Mex twist.


  1. Can I use different types of pasta? Yes, you can substitute spaghetti with other pasta shapes such as penne, rotini, or fusilli, but adjust cooking times accordingly.
  2. Can I make this recipe ahead of time? Yes, you can assemble the casserole ahead of time and refrigerate it, covered, for up to 24 hours before baking. Let it come to room temperature before baking as directed.
  3. Can I use low-fat ingredients to make it healthier? Yes, you can use reduced-fat or low-fat versions of sour cream, soups, and cheese to lower the fat content of the casserole.
  4. Can I omit the breadcrumbs and Parmesan cheese topping? Yes, you can omit the topping if desired, but it adds a crunchy texture and extra flavor to the casserole.
  5. Can I use homemade cream of mushroom and cream of chicken soups? Yes, you can use homemade versions of these soups if you prefer. Just ensure they are well-seasoned and have a creamy consistency.
  6. Can I add other vegetables to the casserole? Absolutely! Feel free to add your favorite vegetables such as peas, carrots, or zucchini to the casserole mixture for extra flavor and nutrition.
  7. Can I use rotisserie chicken instead of cooking chicken? Yes, using rotisserie chicken is a convenient shortcut that saves time. Simply shred the chicken meat and add it to the casserole mixture.
  8. Can I make this recipe gluten-free? Yes, you can use gluten-free spaghetti noodles and breadcrumbs to make the casserole gluten-free. Ensure that all other ingredients are also gluten-free.
  9. Can I freeze the casserole before baking? Yes, you can assemble the casserole, cover it tightly with foil, and freeze it before baking. When ready to bake, thaw it overnight in the refrigerator before baking as directed.
  10. Can I adjust the seasonings to my taste? Absolutely! Feel free to adjust the seasonings such as garlic powder, onion powder, salt, and pepper according to your personal preferences.

With its creamy texture, flavorful blend of spices, and hearty ingredients, Chicken Spaghetti Casserole is a deliciously satisfying meal that’s easy to prepare and sure to please the whole family. Whether you’re looking for a quick weeknight dinner or a crowd-pleasing dish for gatherings, this recipe is a winner. Try it today and experience the irresistible comfort of homemade casserole at its finest!